Longitudinal Cerebral Fetal Baboon MRI Acquisitions for the Study of Cortical Development

Project Acronym: LoFeBa-MRI

Topics: Clinical Fetal Imaging, Database, Anesthesia Protocol, Developmental Pathologies, Brain Development

Disciplinary Fields: Neurosciences, Neuroimaging, Neurocardiology, Medicine, Medical Biology

Summary: The overall topic of LoFeBa-MRU is the study of pre-natal cortical development using Magnetic Resonance imaging (MRI). The project want to provide a unique database of non-human primate (Papio Anubis) longitudinal fetal brain images, with a high temporal resolution: one MR scan a week for the last ten weeks of gestation, period during which cortical folding develops and changes dramatically. To this date, such database does not exist anywhere, and this would provide an exceptional resource for the study of pre-natal brain development, that will be made freely available to the neuroimaging community. In this context, LoFeBa-MRI proposes to perform a pilot project that will demonstrate the feasibility of such database, and prepare the larger project by fine-tuning and optimizing all the critical aspects of such MR acquisitions (anesthesia, animal handling, MR acquisition, data pre-processing).

Project Interlocutor: Olivier Coulon (Institut de Neurosciences de la Timone, UMR 7289)

Project Duration: 05/08/2019 – 11/08/2020

Call of Proposal : Pépinière d’Excellence 2018

Photography Credits: Photo by Timothy Dykes on Unsplash


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