Imagerie photoacoustique de l’activité neuronale en profondeur chez la souris

Project Acronym: PHOTA

Topics: Brain, Cells, Photoacoustic Imaging

Disciplinary Fields: Biology, Optical Imagery, Neurobiology, Acoustics, Physics

Summary: The objective of the PHOTA project is to develop a photoacoustic imaging technique to image neuronal activity at great depths (>1mm) in the brain, particularly in mice. Thanks to an optical measurement of the acoustic field, this technique guarantees a quasi-cellular spatial resolution and a temporal resolution of the order of a millisecond. It provides access to a wide range of fields of view, from a few hundred micrometers to several millimeters. The ability to image the electrical activity of individual neurons at great depths in the brain is likely to have a significant impact in neuroscience.

Project Interlocutor: Thomas Chaigne (Institut Fresnel, UMR 7249, équipe MOSAIC)

Project Duration: 04/20/2019 – 04/20/2021

Call of Proposal: Pépinière d’Excellence 2018

Photography credits: Photo by Robina Weermeijer on Unsplash

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